Kyren Williams anchored the night for the Rams with a versatile, dual-threat performance, while Christian McCaffrey and Puka Nacua supplied the top fantasy fire for SF and LA. Kendrick Bourne flashed a breakout line (10-for-142) and signaled a renewed connection with Mac Jones, amplified by Kyle Shanahan’s scheming. Brock Purdy stayed efficient under pressure, and SF’s receiving corps looked healthier with Jauan Jennings and George Kittle looming as weekly ceiling raisers.

Dak Prescott’s MVP-like start fuels Dallas, while the run games anchor fantasy lines: Javonte Williams benefits from a Jets front that’s been soft to the run, Alvin Kamara remains a consisten RB1 with a sustained workload, and Kyren Williams could surge if Nick Bosa sits. Nico Collins breaks out for Houston against Baltimore’s vulnerable secondary, and Puka Nakua’s historic pace keeps him atop weekly targets. Drake Maye, Daniel Jones, Jordan Addison, and Darren Waller offer high ceilings in favorable matchups as the Week 5 landscape tightens around opportunity and efficiency.

Others receiving votes include Trevor Lawrence and Jared Goff providing upside in smartly contested spots, while the Jets’ backfield remains fluid with Breece Hall’ return and Bree Hall’s status a question mark. This week centers on leveraging workload, game flow, and the few matchup advantages that separate the top fantasy plays from the rest.

Rams scouts debate a buy-low cornerback upgrade, eyeing L'Jarius Sneed as a potential fix for a vulnerable secondary. They weigh asset cost, cap impact, and the upside of pairing him with a higher-support defense, while praising Puka Nacua’s MVP-level production and Kyren Williams’ run-game lift. A Week 5 rematch with the 49ers and Week 4 PFF grades shape the path to a true Super Bowl window.